Osteoarthritis (OA) has a major impact on functioning and independence and ranks among the top ten causes of disability worldwide.
Osteoarthritis is a leading cause of disability and source of economical and societal cost in older adults, amounting to up to 1,7% of GDP in developed nations. This pathology is becoming even more prevalent than in previous decades, as population ages and is faced with challenges of obesity.
We investigate traumatic injury to the musculoskeletal system and in particular cartilage tissues. Traumatic injury exists in its unexpectedness and immediacy, requiring ad-rem therapies. These traumatic injuries often precursor the advent of degenerative disease.